Buy Lorazepam 2mg (Ativan) Online
Ativan (lorazepam), an antianxiety agent, has the chemical formula, 7-chloro-5-(o-chlorophenyl)-1,3dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one and Molecular Weight: 321.16 It is a nearly white powder almost insoluble in water. Similarly, Each Ativan (lorazepam) tablet, to be taken orally, contains 0.5 mg, 1 mg, or 2 mg of lorazepam. Also, the inactive ingredients present are lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.
Clinical Pharmacology of Ativan (lorazepam)
Interestingly, Studies in healthy volunteers show that in single high doses Ativan (lorazepam) has a tranquilizing action. Above all, it acts on the central nervous system with no appreciable effect on the respiratory or cardiovascular systems.
Ativan (lorazepam) is readily absorbed with an absolute bioavailability of 90 percent. Meanwhile, Peak concentrations in plasma occur approximately 2 hours following administration. The peak plasma level of lorazepam from a 2 mg dose is approximately 20 ng/mL.
So far, the mean half-life of unconjugated lorazepam in human plasma is about 12 hours and for its major metabolite, lorazepam glucuronide, about 18 hours.
Indications and Usage
Ativan (lorazepam) is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms. On the other hand, Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.
The effectiveness of Ativan (lorazepam) in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. That is to say, the physician should periodically reassess the usefulness of the drug for the individual patient.
Contraindications of Ativan-Lorazepam
Ativan (lorazepam) -contraindicated in benzodiazepine hypersensitive patients.
Warnings concerning use of Ativan
Concomitant use of benzodiazepines, including Ativan, and opioids may result in profound sedation, respiratory depression, coma, and death. Moreover, because of these risks, reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate.
In patients with depression, a possibility for suicide should be borne in mind
Elderly or debilitated patients may be more susceptible to the sedative effects of lorazepam. The initial dosage should not exceed 2 mg
Most adverse reactions to benzodiazepines. That is to say, the CNS effects and respiratory depression, are dose dependent, with more severe effects occurring with high doses.
For example, in postmarketing experience, overdose with lorazepam has occurred predominantly in combination with alcohol and/or other drugs.
Dosage and Administration
Administer Ativan (lorazepam) orally. The usual range is 2 to 6 mg/day given in divided doses. As such, Take largest dose before bedtime, daily dosage may vary from 1 to 10 mg/day.
For anxiety, most patients require an initial dose of 2 to 3 mg/day given two times a day or three times a day.