Buy Ketamine 50mg/ml injection solution Online
Ketamine is a hallucinogenic dissociative normally sold on the street as a grainy white powder or a clear liquid, when used in medicine. Its sold on the street as a grainy white or brown crystalline powder and tablets, although this is less common.
Why is Ketamine Used Medically?
- Ketamine can provide pain relief and short-term memory loss (for example, amnesia of a medical procedure).
- In surgery, it is used an induction and maintenance agent for sedation and to provide general anesthesia.
- It has also been used for pain control in burn therapy, battlefield injuries, and in children who cannot use other anesthetics due to side effects or allergies.
- Ketamine, through blocking at the N-methyl-D-aspartate (NMDA) site, has rapid action in controlling symptoms of depression and acute suicidal ideation.
- At normal doses, it is often preferred as an anesthetic in patients at risk of bronchospasm and respiratory depression.
Pharmacology of Ketamine
Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, and it blocks HCN1 receptors. However, at higher doses it may also bind to the opioid mu and sigma receptors. It disrupts the neurotransmitter (brain chemical) glutamate. Glutamate is involved with learning, memory, emotion, and pain recognition. It can exhibit sympathomimetic activity which can lead to rapid heart rate and elevated blood pressure.
How is Ketamine Abused?
In addition to its legal, medical uses, ketamine and and synthesized analogs have become drugs of abuse with hallucinogenic properties. It has also been used as a “date rape” drug.
When abused, it is typically insufflated (“snorted” up the nose) in social situations. It is also injected, consumed orally as a liquid, or smoked in marijuana or tobacco.
How Quickly Does Ketamine Work?
- An injection yields a quick response, with effects occurring in seconds to minutes.
- “Snorting” leads to effects in roughly 5 to 15 minutes (this is the most common method of abuse).
- Oral consumption requires between 5 and 30 minutes.
The effects of abuse typically last 1 to 2 hours, but the users judgement, senses and coordination may be affected for up to 24 hours or longer. Sensations the user may seek include floating, stimulation and visual effects.
Ketamine Health Hazards & Side Effects
Abuse of ketamine can be linked with short-term and long-term problems:
- Short-term: Problems with attention, learning, and memory; dreamlike states, hallucinations; sedation; confusion; loss of memory; raised blood pressure; unconsciousness; dangerously slowed breathing.
- Long-term: Ulcers and pain in the bladder; kidney problems; stomach pain; depression; poor memory.
- With an overdose of ketamine, emergency care, such as 911, should be contacted immediately.
- There is no antidote for this drug. Overdose situations are treated with symptomatic and supportive care in the hospital setting. In the emergency department, adverse effects typically resolve in 1 to 3 hours.
- Benzodiazepines such as lorazepam may be used if needed for seizures, excitation, or muscle rigidity.