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Oxycodone

$120.00$580.00

Oxycodone is used to relieve moderate to severe pain. Oxycodone extended-release tablets and extended-release capsules are used to relieve severe pain in people who are expected to need pain medication around the clock for a long time and who cannot be treated with other medications. Oxycodone extended-release tablets and extended-release capsules should not be used to treat pain that can be controlled by medication that is taken as needed. Oxycodone extended-release tablets, extended-release capsules, and concentrated solution should only be used to treat people who are tolerant (used to the effects of the medication) to opioid medications because they have taken this type of medication for at least one week. Oxycodone is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.

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Description

Buy Oxycodone Online

OxyContin® (oxycodone hydrochloride controlled-release) Tablets are an opioid analgesic supplied in 10 mg, 20 mg, 40 mg, 80 mg, and 160 mg tablet strengths for oral administration. The tablet strengths describe the amount of oxycodone per tablet as the hydrochloride salt.

Indication and usage

OxyContin Tablets are a controlled-release oral formulation of oxycodone hydrochloride indicated for the management of moderate to severe pain when a continuous, around-theclock analgesic is needed for an extended period of time.
OxyContin is NOT intended for use as a pre analgesic. Physicians should individualize treatment in every case, initiating therapy at the appropriate point along a progression from non-opioid analgesics, such as non-steroidal antiinflammatory drugs and acetaminophen to opioids in a plan of pain management such as outlined by the World Health Organization, the Agency for Healthcare Research and Quality (formerly known as the Agency for HealthCare Policy and Research), the Federation of State Medical Boards Model Guidelines, or the American Pain Society.

Chemistry of Oxycodone

Non-proprietary name: Oxycodone hydrochloride
Chemical name:4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one hydrochloride
CAS No.: 124-90-3
Molecular formula: C18H21NO4
Molecular weight: 351.83

Contraindications

Hypersensitivity to opioids or any of the constituents of OXYNORM solution for injection or infusion
listed in section 6.1, acute respiratory depression, cor pulmonale, cardiac arrhythmias, acute asthma
or other obstructive airways disease, paralytic ileus, suspected surgical abdomen, severe renal problems.

Special warnings and precautions for use

Oxycodone has to be administered with caution in the debilitated elderly or patients with:
 Severely impaired respiratory function
 Sleep apnoea
 CNS depressants co-administration
 Tolerance, physical dependence and withdrawal
 Psychological dependence (addiction), abuse profile and history of substance and/or alcohol
abuse
 Intracranial lesions, reduced level of consciousness of uncertain origin
 Hypotension
 Pancreatitis
 Myxedema
 Hypothyroidism
 Addison’s disease
 Prostate hypertrophy
 Alcoholism

Tolerance, physical dependence and withdrawal

The patient may develop tolerance to the drug with chronic use and require progressively higher doses to maintain pain control. Prolonged use of this product may lead to physical dependence and withdrawal syndrome may occur upon abrupt cessation of therapy. When a patient no longer requires therapy with oxycodone, it may be advisable to taper the dose gradually to prevent symptoms of withdrawal.

Interaction with other medicines and other forms of interaction

Anticholinergic agents

Antihypertensive agents

CYP2D6 and CYP3A4 Inhibitors and Inducers

Fertility, pregnancy and lactation

Australian Pregnancy Category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human foetus or neonate without causing malformations. These effects may be reversible.
Oxycodone used during pregnancy and labour may cause withdrawal symptoms and/or respiratory depression in the newborn infant. Oral administration of oxycodone during the period of organogenesis did not elicit teratogenicity or embryofoetal toxicity in rats or rabbits at doses up to 8 mg/kg/day in rats.

There are no adequate and well-controlled studies with oxycodone in pregnant women.

Additional information

Quantity( 40mg tablets)

30 tablets, 60 tablets, 90 tablets, 120 tablets, 240 tablets

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