Description
Buy (Oxycontin) Oxycodone Online
Firstly, oxycontin ® (oxycodone hydrochloride controlled-release) Tablets are an opioid analgesic supplied in 10 mg, 20 mg, 40 mg, 80 mg, and 160 mg. The tablet strengths are for oral administration. Above all, the tablet strengths describe the amount of oxycodone per tablet as the hydrochloride salt.
Indication and usage
OxyContin Tablets are a controlled-release oral formulation of oxycodone hydrochloride indicated for the management of moderate to severe pain. Consequently, are used when a continuous, around-theclock analgesic is needed for an extended period of time. Certainly, you can buy oxycontin for sale online, cheap prices in USA. Equally, discrete oxycontin overnight shipping with secured payment btc, cashapp, credit cards.
OxyContin NOT intended as a pre analgesic. Moreover, Physicians should individualize treatment in every case, initiating therapy at the appropriate point along a progression from non-opioid analgesics, such as non-steroidal antiinflammatory drugs and acetaminophen to opioids. For example, in a plan of pain management such as outlined by the World Health Organization, the Agency for Healthcare Research and Quality (formerly known as the Agency for HealthCare Policy and Research), the Federation of State Medical Boards Model Guidelines, or the American Pain Society.
Chemistry of Oxycontin
Non-proprietary name: Oxycodone hydrochloride
Chemical name:4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one hydrochloride
CAS No.: 124-90-3
Molecular formula: C18H21NO4
Molecular weight: 351.83
Contraindications
Hypersensitivity to opioids or any of the constituents of OXYNORM solution for injection or infusion. acute respiratory depression, cor pulmonale, cardiac arrhythmias, acute asthma
or other obstructive airways disease, paralytic ileus, suspected surgical abdomen, severe renal problems.
Oxycontin special warnings and precautions for use
Oxycodone has to be administered with caution in the debilitated elderly or patients with:
Severely impaired respiratory function, Sleep apnoea, CNS depressants co-administration, Tolerance, physical dependence and withdrawal.
Psychological dependence (addiction), abuse profile and history of substance and/or alcohol
abuse
Intracranial lesions, reduced level of consciousness of uncertain origin, Hypotension, Pancreatitis, Myxedema
Equally, Hypothyroidism due to oxycontin, Addison’s disease, Prostate hypertrophy, Alcoholism
Tolerance, physical dependence and withdrawal
The patient may develop tolerance to the drug with chronic use and require progressively higher doses to maintain pain control. Prolonged use of this product may lead to physical dependence and withdrawal syndrome may occur upon abrupt cessation of therapy. When a patient no longer requires therapy with oxycodone, it may be advisable to taper the dose gradually to prevent symptoms of withdrawal.
Interaction of oxycontin with other medicines and other forms of interaction
Anticholinergic agents
Antihypertensive agents
CYP2D6 and CYP3A4 Inhibitors and Inducers
Fertility, pregnancy and lactation
Australian Pregnancy Category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human foetus or neonate without causing malformations. Certainly, these effects may be reversible.
Oxycodone used during pregnancy and labour may cause withdrawal symptoms and/or respiratory depression in the newborn infant. However, Oral administration of oxycodone during the period of organogenesis did not elicit teratogenicity or embryofoetal toxicity in rats or rabbits at doses up to 8 mg/kg/day in rats.
In conclusion, there are no adequate and well-controlled studies with oxycodone in pregnant women.
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