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Vardenafil

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Vardenafil is an oral drug that is used to treat impotence, the inability to attain or maintain a penile erection. It has a mechanism of action that is similar to sildenafil (Viagra), and tadalafil (Cialis).

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Description

Buy Levitra (Verdanafil) Tablets Online

What is Verdanafil

LEVITRA (vardenafil hydrochloride) is administered orally for the treatment of erectile dysfunction. This monohydrochloride salt of vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

Vardenafil HCl is designated chemically as piperazine, 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-, monohydrochloride

Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase in size and increase the delivery of blood to the penis. At the same time, the blood vessels carrying blood away from the penis decrease in size and decrease the removal of blood from the penis. Sexual stimulation that leads to the engorgement and erection causes the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase to produce cyclic guanosine monophosphate (cGMP). The cGMP is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the penis, respectively. Vardenafil prevents an enzyme called phosphodiesterase-5 (PDE-5) from destroying cGMP so that cGMP persists longer. The longer cGMP persists, the more prolonged the engorgement of the penis. Vardenafil was approved by the FDA in August 2003.

What brand names are available for vardenafil?

Levitra, Staxyn ODT

LEVITRA is formulated as red, round, film-coated tablets with “MYLAN” cross debossed on one side and “2.5”, “5”, “10”, and “20” on the other side corresponding to 2.5 mg, 5 mg, 10 mg, and 20 mg of vardenafil, respectively. In addition to the active ingredient, vardenafil HCl, each tablet contains microcrystalline cellulose, crospovidone, colloidal silicon dioxide, magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, yellow ferric oxide, and red ferric oxide

Is vardenafil available as a generic drug?

No

Do I need a prescription for vardenafil?

Yes, Just like viagra and Cialis

What are the side effects of vardenafil?

The most common side effects of vardenafil are facial flushing (reddening), headaches, stomach upset, diarrheaflu like symptoms, and nausea. Vardenafil also may cause chest painlow blood pressureblurred vision and changes in color vision, abnormal ejaculation and priapism (painful erection lasting more than 6 hours). Patients should seek immediate medical help if they experience an erection lasting more than 4 hours.

What is the dosage for vardenafil?

For most individuals, the recommended dose of vardenafil regular tablets is 10 mg per day taken 60 minutes before intercourse. If there is no response or side effects, the dose may be increased to 20 mg or, if there are side effects, it may be reduced to 5 mg.

Individuals 65 years of age or older should begin therapy with 5 mg.

Orally disintegrating tablets (ODT) are not interchangeable with regular vardenafil tablets because they are better absorbed and produce higher blood levels than regular tablets. The recommended dosing when using ODT is one tablet 60 minutes before intercourse. Only one tablet should be used per day. It should be placed on the tongue until it disintegrates and should not be swallowed with water.

Which drugs or supplements interact with vardenafil?

The breakdown and elimination of vardenafil from the body is inhibited by erythromycinclarithromycin (Biaxin), ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan), ritonavir (Norvir), atazanavir (Reyataz), grapefruit juice. Therefore, these drugs increase the concentration of vardenafil in the blood and should not be combined with vardenafil. Vardenafil reduces the concentration of ritonavir and indinavir and may reduce the effect these drugs.

Is vardenafil safe to take if I’m pregnant or breastfeeding?

Vardenafil is not approved for use in women.

Vardenafil has not been evaluated in women who are breastfeeding.

What else should I know about vardenafil?

What preparations of vardenafil are available?

Tablets: 2.5, 5, 10 and 20 mg. Tablet (orally disintegrating): 10 mg.

How should I keep vardenafil stored?

Vardenafil should be stored at room temperature between 15-30 C (59-86 F).

Additional information

Quantity

30 tablets, 60 tablets, 90 tablets, 120 tablets

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